Research progress on active components and anticancer molecular mechanism of Huaier
Huaier(Trametes robinophila Murr.)is a kind of Chinese herbal medicine,which has shown good effects in the clinical treatment of various tumors.By summarizing the latest research progress in anticancer of Huaier in recent years,this review describes the main active components of Huaier,including its crusade substances,polysaccharides and other active substances;research on Huaier in lung cancer,liver cancer,breast cancer,digestive tract cancers and other malignant tumors and anti-tumor mechanism,including inhibition of proliferation and metastasis,blockade of cell cycle,induction of apoptosis and autophagy,anti-angiogenesis in tumors,enhancement of tumor immunogenic microenvironment,etc;and problems that need to be solved urgently in the clinical application and combined drug use of Huaier.This paper aims to provide a reference for the large-scale clinical application of Huaier in the future by discussing the above three aspects.
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