Research progress and clinical application prospect of fecal microbiota transplantation in the treatment of children with extraintestinal diseases
The gut microbiota influences human physiological status and nutritional absorption and metabolism.Fecal microbiota transplantation(FMT)is an emerging therapeutic tool to reshape the structure of the intestinal flora and thereby regulate the human intestinal microbiota by transplanting functional flora from healthy human faeces into patients.This paper reviewed the recent application and progress of fecal transplantation for extraintestinal diseases such as metabolic diseases,allergic diseases and autism spectrum disorders in children,showing that FMT is safe and effective in modifying intestinal pathophysiology and has the potential to be a promising technique for the treatment of many paediatric diseases.We reviewed the application status and prospect of FMT in children and adolescents with extraintestinal diseases.
fecal microbiota transplantationchildren and adolescentsclinical application