首页|雷公藤治疗类风湿关节炎

雷公藤治疗类风湿关节炎

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雷公藤有黄藤木、断肠草、蒸龙草、震龙根等别称,具有祛风除湿、活血通络、消肿止痛的作用.雷公藤作为治疗类风湿关节炎常用药的历史源远流长.类风湿关节炎(rheumatoid arthritis,RA)是一种自身免疫病,以侵蚀性关节炎为主要特征,其病理基础是滑膜炎,主要表现为关节肿胀和疼痛.本文先分别叙述雷公藤和类风湿,最后对近年来雷公藤治疗类风湿的临床研究和作用机制进行综述,以期为临床治疗RA的提供理论参考.
Roles of Tripterygium wilfordii in the treatment of rheumatoid arthritis
The traditional Chinese medicine Tripterygium wilfordii has other names,such as Huangtengmu,Broken Intestine Herb,Steamed Dragon Herb and Zhenlong Root.It has the functions of dispelling wind,removing dampness,activating blood circulation,clearing collaterals,and relieving swelling and pain.Tripterygium wilfordii has a long history as a common medicine for the treatment of rheumatoid arthritis.Rheumatoid arthritis(RA)is an autoimmune disease characterised by erosive arthritis,the pathological basis of which is synovitis,manifested mainly by joint swelling and pain.This work first describes Tripterygium wilfordii and rheumatoid arthritis,and finally summarizes the clinical research and mechanism of Tripterygium wilfordiiin the treatment of RA in recent years,aimed to provide theoretical reference for the clinical treatment of RA.

traditional Chinese medicineTripterygium wilfordiiadverse reactionsrheumatoid arthritis

翁慧敏、李宁、张婧娴、姚俊、金文野、张叶琪、潘慧婕、李斌、李丹、孙阳、谢东浩

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上海中医药大学,上海 201203

上海市光华中西医结合医院药剂科,上海 200052

上海中医药大学附属龙华医院,上海 200032

上海交通大学医学院,上海市免疫学研究所,上海 200025

上海市中医药研究院中西医结合关节炎研究所,上海 200052

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中药 雷公藤 不良反应 类风湿关节炎

上海市自然科学基金上海市青年科技英才扬帆计划

20ZR144770020YF1441600

2023

生命的化学
中国生物化学与分子生物学会

生命的化学

CSTPCD
影响因子:0.404
ISSN:1000-1336
年,卷(期):2023.43(2)
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