The incidence of colorectal cancer has increased year by year,despite research progress in chemoradiotherapy and surgery,its recurrence rate remains high.Compared to other types of cancer,survival rates for colorectal cancer patients,although increased,lasted only for a relatively short period of time(20 months).RUNX proteins belong to a family of transcription factors and play a key role in different types of cancer.This review will analyze the mechanism of the RUNX family in the development and progression of colorectal cancer and show its importance as a cancer biomarker.In addition,the importance of continuing the dual function studies of RUNX proteins will be emphasized,in order to apply them in the specific diagnosis and treatment of colorectal cancer.
万方数据
维普
