The protective effect of emodin against inflammatory diseases of the lung
Emodin is the main active monomer component of Chinese medicine rhubarb,which belongs to the free type anthraquinone substance.Modern pharmacology has shown that emodin has various pharmacological activities such as anti-inflammatory,anti-oxidative stress,anti-bacterial,anti-fibrotic,immunomodulatory and anti-tumor.In recent years,both in vitro and in vivo experiments have demonstrated that emodin has a good effect on acute lung injury(ALI),pulmonary fibrosis asthma,other lung inflammatory diseases,including inhibiting inflammatory signaling pathways and inflammatory cell infiltration,reducing pulmonary edema,improving fibrosis,and relieving lung or airway inflammation.Therefore,this paper mainly summarizes the relevant studies of emodin for the treatment of ALI,pulmonary fibrosis and asthma from the perspective of mechanism,in order to provide some theoretical basis for the in-depth study of rhodopsin for the treatment of inflammatory diseases in the lung.
万方数据
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