Reactive oxygen species(ROS)are a class of chemically active substances containing oxygen.In recent years,with the discovery of multiple ROS-related signaling pathways,ROS,as an important metabolite in the body,has been found to play important roles in regulating cell signal transduction and maintaining homeostasis.At present,it is believed that tumor cells often have relatively high ROS levels due to their vigorous metabolism,and the development of new anti-tumor approaches by leveraging the ROS level in tumor cells is considered as an important direction for the treatment of tumors.This paper will provide a comprehensive review on the origin of ROS and their correlation with tumors,their anti-tumor mechanisms,and roles in tumor treatment as well as their application in tumor diagnosis.
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