Research progress of the correlation pathogenesis between endometriosis and endometrial polyp
Endometriosis(EMT)and endometrial polyp(EP)are two common benign gynecological diseases,with the primary pathological symptom of abnormal implantation or hyperplasia of endothelial tissue.Epidemiological data show that the incidence of EP in patients with EMT is gradually increasing,and the risk of patients with EP in combination with EMT is also increasing year by year,indicating a close correlation and intrinsic link between them.Although the pathogenesis of both has not been fully determined,recent studies have shown that the pathogenesis of EMT and EP may be related to long-term high levels of estrogen stimulation,an imbalance between estrogen receptors and progesterone receptors,abnormal apoptosis and proliferation,expression of cytokines,local chronic inflammatory stimulation,dysregulation of the immune system,oxidative stress,microbiota disorders and metabolic abnormalities.They share a set of risk factors,probably participating in each other's disease process,thus showing a negative influence on clinical treatment.We review the correlation pathogenesis of EMT and EP,which are expected to provide more rationale for the basic research and clinical treatment.
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