Role of NO/ROS redox balance in cardiovascular diseases
NO/ROS redox balance is closely related to cell homeostasis,function and signal transduction.The overproduction of reactive oxygen species(ROS)or the decrease of nitric oxide(NO)and its bioavailability will cause redox imbalance and lead to a series of cardiovascular diseases.As an important gas signaling molecule,NO is involved in the maintenance of redox balance and related physiological and pathological processes.NO donor compounds and controllable delivery systems show great promise in the biomedical field.In this paper,the intracellular NO/ROS redox balance and its relationship with cardiovascular diseases,biomaterials with NO release and(or)ROS scavenging function and their applications will be summarized and prospected.
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