Relationship between estrogen receptor ERα on methylation and renal related diseases
As an important physiological hormone,estrogen is related to the occurrence and development of many diseases.In recent years,studies have found that estrogen can regulate the kidney through estrogen receptor.Estrogen receptor α distributed in multiple areas related to the kidneys in the body,and the abnormal methylation of estrogen receptor will affect the regulation of estrogen on the kidney,leading to osteoporosis,diabetes nephropathy and other kidney related diseases.This paper summarizes ERα the physiological structure,methylation process,and research progress on some kidney diseases,in order to elucidate ERα the regulatory effect of methylation on renal diseases and the discovery of the interaction mechanism between cross pathway proteins of different kidney diseases,provide further theoretical support for clinical treatment.
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