Research progress of miRNA in autoimmune myocarditis
Autoimmune myocarditis(AMC)is often caused by cellular and humoral immune dysfunction in the body,leading to infiltration of inflammatory cells around myocardial tissue,triggering an autoimmune response,and gradually developing into chronic injury and dilated cardiomyopathy,seriously affecting the prognosis of patients.MicroRNA(miRNA)is often dysregulated in autoimmune myocarditis,regulating gene expression or immune cell activation and differentiation,and participating in regulating the growth and apoptosis of myocardial cells.This review briefly elaborates on the research progress and existing problems of miRNA in autoimmune myocarditis from its potential mechanism,diagnostic and prognostic biomarkers,and treatment.
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