The role of m6A modification in skeletal muscle myogenesis and traditional Chinese medicine method for skeletal muscle injury regeneration
Skeletal muscle is the main organ of the human motor system,and damage to skeletal muscle can reduce quality of life and worsen disease.Exploring skeletal muscle regeneration and repair is essential to restore and maintain muscle function.N6-methyladenosine modification is an important mRNA methylation modification in eukaryotes,and its role in regulating skeletal muscle production is compatible with the traditional Chinese medicine invigorating the spleen and tonifying the kidney to nourish muscle growth.This paper summarizes the roles of m6A methylation modification-related homologous factors methyltransferases,demethylases and recognition proteins in myogenesis,and discusses their correlation with traditional Chinese medicine theory and the application of traditional Chinese medicine therapy in myogenesis,which provides theoretical basis and research ideas for in-depth study of the molecular mechanism of skeletal muscle repair and regeneration and traditional Chinese medicine regulates myogenesis through m6A modification.
万方数据
维普
