Long non-coding RNA(lncRNA)is a type of non-coding RNA molecules with transcripts greater than 200 nucleotides in length and are widely involved in important life processes such as cell proliferation,differentiation,apoptosis and chromatin remodelling.Numerous studies have confirmed that lncRNAs can exist stably in the circulation,and their expression levels are closely related to the occurrence,development and prognosis of digestive tract tumor.In this paper,we briefly review the recent advances in the study of circulating blood lncRNA in digestive tract tumor,and focus on the clinical application of circulating blood lncRNA in the diagnosis and prognosis assessment of digestive tract tumor and new techniques for their detection.
关键词
长链非编码RNA/消化道肿瘤/循环血
Key words
long non-coding RNA/digestive tract tumor/circulating blood
维普
万方数据