生命的化学2023,Vol.43Issue(11) :1691-1698.DOI:10.13488/j.smhx.20230648

PRP与创伤性关节炎治疗

PRP in the treatment of post-traumatic osteoarthritis

张辰 赵军 徐世红 姜朝阳 王培鑫 李玙璠 朱欢
生命的化学2023,Vol.43Issue(11) :1691-1698.DOI:10.13488/j.smhx.20230648

PRP与创伤性关节炎治疗

PRP in the treatment of post-traumatic osteoarthritis

张辰 1赵军 2徐世红 2姜朝阳 2王培鑫 1李玙璠 1朱欢1
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作者信息

  • 1. 甘肃中医药大学中医临床学院,兰州 730000
  • 2. 甘肃省中医院,兰州 730050
  • 折叠

摘要

创伤性关节炎的发病呈上升趋势,已经严重危害到患者的健康.目前,创伤性关节炎的治疗途径主要有口服药物治疗、关节重建手术治疗等,但均因不良反应明显、二次创伤存在一定的缺陷,创伤性关节炎的治疗进入一个平台期.近年来,富血小板血浆以其自身细胞制备而免疫反应少的优势在医学领域得到广泛应用,尤其在创伤性关节炎方面具有显著疗效.大量临床研究已证实,富血小板血浆治疗创伤性关节炎可以有效减少滑膜炎症,保护软骨,减轻疼痛,恢复关节结构和功能.本文将对富血小板血浆治疗创伤性关节炎的最新研究进展进行综述,以期为创伤性关节炎的临床治疗提供参考.

Abstract

At present,the incidence of post-traumatic osteoarthritis is on the rise,which seriously endangers the health of patients.At present,the treatment of post-traumatic osteoarthritis mainly includes oral drug therapy,joint reconstruction surgery,and other ways,but due to obvious side effects and certain defects in secondary trauma,the treatment of post-traumatic osteoarthritis has entered a plateau.In recent years,platelet-rich plasma has been widely used in the medical field due to the advantages of its own cell production and low immune response,especially in post-traumatic osteoarthritis.A large number of clinical studies have confirmed that PRP treatment of post-traumatic osteoarthritis can effectively reduce synovial inflammation,protect cartilage,reduce pain,and thus restore joint structure and function.This paper will review the latest research progress of PRP in the treatment of post-traumatic osteoarthritis,to provide a reference for the clinical treatment of post-traumatic osteoarthritis.

关键词

富血小板血浆/创伤性关节炎/骨关节炎

Key words

platelet rich plasma/post-traumatic osteoarthritis/osteoarthritis

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基金项目

甘肃省202重点人才项目(2022RCXM023)

甘肃省中医药科研课题重点课题(GZKZ-2021-4)

甘肃省科技计划项目(21JR7RA681)

兰州市人才创新创业项目(2020-RC-55)

甘肃省科技计划项目重点研发计划(22YF7FA104)

出版年

2023
生命的化学
中国生物化学与分子生物学会

生命的化学

CSTPCD
影响因子:0.404
ISSN:1000-1336
参考文献量10
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