Marine biotoxins are a type of highly active special metabolic component that originates from toxic marine organisms.Its unique and novel chemical structure has resulted in its special damage mechanism to organisms and severe toxic effects.Although some progress has been made in the study of the mechanisms underlying marine biotoxin-induced damage,particularly with regard to ion channels,there are still many mechanisms that remain unclear.Therefore,further exploration of the mechanisms underlying marine biotoxin-induced damage is essential.This will not only help to prevent marine biotoxin poisoning but also have the potential to transform these toxins into new"marine drugs".This article provides an overview of the reported mechanisms of marine biotoxin toxicity,including their direct effects on various ion channels on cell membranes,interfering with the intracellular protein phosphorylation process,disrupting mitochondrial functions,inducing inflammatory and immune responses,and even causing cell death,which can serve as a reference for future in-depth research.
marine biotoxinsdamage mechanismion channelprotein phosphorylationmitochondrial function