Research progress on molecular mechanism of PM2.5 affecting type 2 diabetes
Exposure of atmospheric PM2.5 pollution has a variety of adverse effects on human health,among which promoting the occurrence and development of diabetes is an important way to affect health.In this review,after elaborating that PM2.5 affects the occurrence and development of type 2 diabetes mainly through molecular mechanisms,such as oxidative stress,inflammatory reaction,mitochondrial dysfunction and endoplasmic reticulum stress,we have also discussed that ferroptosis might participate in the process of the occurrence and development of type 2 diabetes caused by PM2.5 exposure,and pointed out that it was urgent to further study the underlying molecular mechanisms of the occurrence and development of type 2 diabetes caused by PM2.5.The aim is to provide basic scientific information for both scientific decision-making of the relevant departments and newcomers in this researching field.