Roles in functional metabolomics in acute kidney injury
Acute kidney injury(AKI)is a clinical syndrome of rapid decline in renal function caused by multiple factors.There aren't many effective treatments available in clinical practice,and its pathophysiology is complicated.In recent years,functional metabolomics has become a new research focus to explore the pathogenesis of AKI.Functional metabolomics,in contrast to standard metabolomics,uses the identification of distinct metabolites in disease to clearly define the pathophysiological process of disease occurrence.In order to provide a theoretical foundation for the early prevention and treatment of AKI,this study highlights the scientific development of many areas of metabolomics in AKI,focusing on modifications of metabolite regulating molecular pathways.