Progress in the sorting and signaling pathways of breast cancer stem cells
Cancer stem cells are a group of cells in tumor tissue which have properties of stem cells and the ability of both mlti-directional differentiation and self-renewing.In recent years,with the concept of cancer stem cells proposed,much work has been focused on breast cancer stem cells (BCSC).Understanding how to sorting BCSC and how to maintain the "stem" is crucial for treatment and prevention of breast cancer.In this paper,the progress in sorting of BCSC,related signaling pathways and epithelial-mesenchymal transition (EMT) is summarized.
breast cancer stem cellssorting of stem cellssignaling pathway