Development trend of integrative biology field in 2023
Since the mid-20th century,life science research has gradually extended from the individual organism level to different levels such as cells,molecules,and genes.Faced with the complexity and diversity of living organisms,there is an increasing emphasis on cross-level,multidimensional,and lifelong structural and functional studies in life sciences.The emergence of integrative biology aims to reveal the relationships and regulatory mechanisms among various levels within organisms,with the goal of gaining a deeper understanding of the functions and behaviors of living organisms.Looking back on the decades-long development of integrative biology,interdisciplinary tools have provided robust support,and the emergence of cross-level functionalities has been a key juncture in its research.The revelation of scientific complexities such as non-linearity,uncertainty,and heterogeneity serves as the theoretical foundation that empowers solutions for life and health challenges.In 2023,integrative biology achieved remarkable breakthroughs in exploring emergent phenomena,health,and ecological environments within life systems.These advancements not only enhanced our comprehensive understanding of the life sciences but also facilitated a thorough grasp of the physiological and pathological changes in organisms,encompassing both states of health and disease.Looking ahead,integrative biology may,with its more comprehensive perspective,delve into the complexity of life systems,variations in critical conditions,and the transitions between unordered and ordered states.This,in turn,may facilitate a deeper human understanding of the essence of life,fostering unprecedented technological strategies.