Recent progress in neoadjuvant therapy for locally advanced esophageal cancer
Esophageal cancer is one of the tumors with high malignancy and poor prognosis in the worldwide.Surgical treatment is the first-choice for the locally advanced esophageal cancer,but simple surgical treatment is not effective and the overall 5-year survival rate remains low.Therefore,the treatment of locally advanced esophageal cancer is more inclined to be surgery combined with multiple modes of treatment.In locally advanced esophageal cancer,neoadjuvant therapy has demonstrated significant survival benefits,good clinical efficacy,and acceptable toxic reactions,becoming one of the standard treatment modes.Neoadjuvant therapy mainly includes neoadjuvant chemotherapy,neoadjuvant radiotherapy and chemotherapy and neoadjuvant immunotherapy.This article reviews the research progress of neoadjuvant therapy in locally advanced esophageal cancer.
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