Research progress on nutrition intervention for type 2 diabetes mellitus based on intestinal flora
Type 2 diabetes mellitus(T2DM)is mainly characterized by persistent hyperglycemia,influenced by many risk factors.Intestinal microbiota is a huge system,composed of bacteria,archaea,viruses,and eukaryotic microbes in human intestinal tract,which participates in and affects material and energy metabolism.Studies have shown that intestinal flora can indirectly cause insulin resistance and reduce insulin sensitivity by affecting short-chain fatty acids,bile acids,branched-chain amino acids,lipopolysaccharides,etc.,thus affecting the occurrence and development of T2DM.Nutrition intervention is the basic method for treating diabetes,which can effectively regulate the balance of intestinal flora to maintain homeostasis,indirectly regulate the production of insulin,and effectively improve blood sugar.This article reviews the pathogenesis of T2DM,and analyzes the research progress of intestinal flora intervention by nutrition to improve T2DM,aiming to provide new ideas for treating T2DM through regulating intestinal flora,and to provide a reference for precise personalized nutrition intervention.
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