Pathogenesis of enterogenic mastitis in dairy cows and its prevention and control by short chain fatty acids
Dairy mastitis is a disease affecting dairy herds,which seriously restricts the development of dairy industry.Mastitis is generally considered to be a local inflammation caused by pathogenic bacteria invading the mammary gland through the mammary duct,and recent studies have found that the endogenous"gut-mammary gland"axis in dairy cows plays an equally important role in inducing mastitis,that is,enterogenous mastitis.Therefore,targeted regulation of gastrointestinal tract may be an effective way to prevent and control"enterogenous mastitis".Short chain fatty acids(SCFAs)are a new dietary substance that can maintain gastrointestinal flora homeostasis,restore blood-milk barrier permeability,and inhibit the development of mammary gland inflammation.Targeting SCFAs to regulate the gut-mammary axis can effectively prevent and treat enterogenic mastitis in dairy cows.The pathogenesis of enterogenic mastitis in dairy cows and the prevention and control effects of SCFAs were reviewed in this paper,in order to provide new ideas for the prevention and control of enterogenous mastitis in dairy cows.