Prospects and bottlenecks in development and industrialization of protein biochips
Development of biochip technology remains a great challenge.Unlike gene biochip,the research and development and industrialization of protein biochip yet runs on a way covered with thorns as a result of influence by intrinsic three-dimensional construction and sustainable biological activity of on-chip proteins,stabilization of surface chemical modification on solid supports and methodology of detection and analysis.In this review,we have a brief review on types of protein biochips,surface chemical modification,manufacturing processes,and current R&D status,main shackles and potential trends in biochip research and development.
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