Research progress of microbially derived radiation protection agents
The increasing prevalence of radiation technology has led to a parallel rise in the research and demand for radiation damage protection and medical treatments.Radiation damage protection agents represent one of the most effective and direct means of saving and protecting against radiation damage.In the past,research and development of radiation damage protection products has been based on plants,animals,chemical synthesis,and microorganisms.Nevertheless,microorganisms have seldom been employed as research subjects.It is certain that one of the Earth's most radiation-resistant life forms is microorganism.Consequently,they are an ideal target and source for the development of radiation damage protection agents.The objective of this review is to provide insight into the current state of research in the field of radiation damage protection agents of microbial origin,with an emphasis on the specific research progress and current status of radiation damage protection agents of bacterial,fungal,and archaeal origin.In particular,functions of antioxidant and anti-radiation agents are analysed,including pseudohyphae,melanin,MAAs,MDP,CBLB502,and carotenoids.Furthermore,we present an in-depth analysis of the existing problems and targeted research directions,aiming to provide a scientific basis for the research and development of new microbial-derived radiation protection agents.
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