生命科学仪器2024,Vol.22Issue(1) :56-58.DOI:10.11967/2024220218

基于"阳微阴弦"病机自拟温肾祛弦颗粒治疗微血管性心绞痛临床观察

ClinicalObservation on the Treatment of Microvascular Angina Pectoris by Self-prepared Wenshenquxian Granule based on the Pathogenesis of"Yang Wei Yin Xian"

杨瑞彤 齐锋 宋柏奇
生命科学仪器2024,Vol.22Issue(1) :56-58.DOI:10.11967/2024220218

基于"阳微阴弦"病机自拟温肾祛弦颗粒治疗微血管性心绞痛临床观察

ClinicalObservation on the Treatment of Microvascular Angina Pectoris by Self-prepared Wenshenquxian Granule based on the Pathogenesis of"Yang Wei Yin Xian"

杨瑞彤 1齐锋 2宋柏奇3
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作者信息

  • 1. 长春中医药大学研究生学院
  • 2. 长春中医药大学附属医院,吉林长春 130000
  • 3. 长春二道区人民医院,吉林长春 130000
  • 折叠

摘要

目的 观察中药温肾祛弦颗粒治疗阳虚痰瘀互结型微血管性心绞痛患者的临床疗效.方法 选取2021年1-11月在医院门诊及疗区治疗的阳虚痰瘀互结型微血管性心绞痛患者60例,随机分为治疗组与对照组.治疗组给予温肾祛弦颗粒治疗,对照组给予尼可地尔治疗.对比两组中医证候临床疗效、生活质量、心电图踏车负荷试验疗效.结果 治疗组中医证候治疗有效率高于对照组,差异有统计学意义(P<0.05).治疗组治疗后躯体活动受限程度、心绞痛稳定状态、心绞痛发作情况、治疗满意程度、疾病认知程度评分均高于对照组,差异有统计学意义(P<0.05).两组电图踏车负荷试验总有效率对比,差异无统计学意义(P>0.05).结论 中药温肾祛弦颗粒治疗阳虚痰瘀互结型微血管性心绞痛在改善患者中医证候、生活质量及心脏负荷等方面均具有显著疗效.

Abstract

Objective:To observe the clinical effect of Wenshen Quxian Granule on microvascular angina pectoris with yang deficiency and phlegm and blood stasis.Methods:60 cases of microvascular angina pectoris with yang defi-ciency and phlegm and blood stasis were selected from January to November,2021,and were randomly divided into treatment group and control group.The treatment group was treated with Wenshen Quxian Granule,while the con-trol group was treated with nicorandil.The clinical efficacy,quality of life,and ECG treadmill load test were com-pared between the two groups.Results:The effective rate of TCM syndrome treatment in treatment group was high-er than that in control group,and the difference was statistically significant(P<0.05).After treatment,the scores of physical activity limitation,stable state of angina pectoris,angina pectoris attack,treatment satisfaction and dis-ease cognition in the treatment group were higher than those in the control group,and the difference was statistical-ly significant(P<0.05).There was no significant difference in the total effective rate of treadmill load test between the two groups(P>0.05).Conclusion:Wenshen Quxian Granule,a traditional Chinese medicine,has a significant effect on improving TCM syndromes,quality of life and heart load in treating microvascular angina pectoris with yang deficiency and phlegm and blood stasis.

关键词

阳微阴弦/微血管性心绞痛/临床观察

Key words

Yang Wei Yin Xian/MICRO VASCULAR ANGINA PECTORIS/CLINICAL OBSERVATION

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基金项目

吉林省中医药局项目(2021054)

出版年

2024
生命科学仪器
北京市北分仪器技术公司

生命科学仪器

影响因子:0.305
ISSN:1671-7929
参考文献量8
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