Comparison of Curative Effect between Unilateral Double-channel Endoscope and Minimally Invasive Lumbar Interbody Fusion in the Treatment of Lumbar Degenerative Diseases and its Influence on Pain Medium
Objective:To compare the curative effect of unilateral dual-channel endoscope(UBE)and minimally in-vasive tubular(Mis)in the treatment of lumbar degenerative diseases and its influence on pain media.Methods:Eighty-two patients with lumbar degenerative diseases admitted to the Department of Orthopaedics of the First People's Hospital of Zhangjiagang City from February 2020 to May 2023 were analyzed retrospectively.They were divided into Mis-TLIF group(42 cases)and UBE-TLIF group(40 cases)according to different treatment schemes.The operation situation,postoperative complications,postoperative pain,degree of dysfunction and pain medium level were compared between the two groups.Results:Compared with Mis-TLIF group,UBE-TLIF group had a slightly longer operation time,but less intraoperative bleeding and postoperative drainage,and shorter hospital stay,with statistical significance(P＜0.05).There was no significant difference in the follow-up time be-tween the two groups(P＞0.05).There was no significant difference between the two groups(P＞0.05).Before operation,there was no significant difference in VAS score and ODI score between the two groups(P＞0.05).The VAS and ODI scores of both groups were improved after operation,and the VAS and ODI scores of UBE-TLIF group were lower than those of Mis-TLIF group one month after operation,the difference was statistically signifi-cant(P＜0.05).At 3 months,6 months and the last follow-up,there was no significant difference in VAS and ODI scores between the two groups(P＞0.05).Before operation,the levels of SP,PGE2_2 and β-EP were not significantly different(P＞0.05).Three days after operation,the SP level in UBE-TLIF group was higher than that in Mis-TLIF group,and the PGE2 and β-EP levels were lower than that in Mis-TLIF group,with statisti-cal significance(P＜0.05).There was no significant difference in the incidence of complications between the two groups(P＞0.05).Conclusion:UBE-TILF can achieve the same clinical effect as Mis-TLIF in the treatment of lumbar degenerative diseases,and it also has the advantages of less intraoperative blood loss and shorter postopera-tive hospitalization time,and the short-term effect is better.
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