PFNA-Ⅱ髓内钉治疗股骨转子间骨折对患者髋关节功能及血清炎症因子的影响
Effect of PFNA-Intramedullary Nail for Intertrochanteric Fracture on Hip Function And Serum Inflammation
孔丹辉 1陈金亮 1夏炎 1成欣 1郑鸿鸣1
作者信息
- 1. 丹阳市人民医院骨科,江苏丹阳 212300
- 折叠
摘要
目的 探讨PFNA-Ⅱ髓内钉治疗股骨转子间骨折对患者髋关节功能及血清炎症因子的影响.方法 选择2020年1月-2022年12月丹阳市人民医院收治的股骨转子间骨折患者88例,以随机双盲方式分为对照组与观察组,各44例.对照组采用动力髋螺钉治疗,观察组采用PFNA-Ⅱ髓内钉治疗.对比两组围手术期相关指标、髋关节功能、血清炎症因子及术后并发症.结果 观察组手术时长、切口长度、住院时间及骨折愈合时间均短于对照组,术中出血量少于对照组,差异有统计学意义(P<0.05).术后1个月、3个月、6个月,观察组Harris评分均高于对照组,血清TNF-α、IL-6及IL-1β水平均低于对照组,差异有统计学意义(P<0.05).两组术后并发症发生率比较,差异无统计学意义(P>0.05).结论 采用PFNA-Ⅱ髓内钉治疗股骨转子间骨折患者可减轻其手术创伤,缩短其术后恢复时间,改善其髋关节功能,减轻其机体炎症反应.
Abstract
Objective:To Objective to investigate the effect of pfna-ⅱ intramedullary nail on hip joint function and serum in-flammatory factors in patients with intertrochanteric fracture.Methods:Eighty-eight patients with intertrochanteric frac-ture of femur admitted to Danyang People's Hospital from January 2020 to December 2022 were randomly and double-blind divided into control group and observation group,44 cases in each group.The control group was treated with dynamic hip screw,and the observation group was treated with PFNA-Ⅱ intramedullary nail.The perioperative related indexes,hip function,serum inflammatory factors and postoperative complications were compared between the two groups.Results:The operation duration,incision length,hospitalization time and fracture healing time in the observation group were shorter than those in the control group,and the amount of bleeding during the operation was less than that in the control group,with statistical significance(P<0.05).At 1 month.3 months and 6 months after operation,the Harris score in the obser-vation group was higher than that in the control group,and the serum levels of TNF-α,IL-6 and IL-1β were lower than those in the control group,with statistical significance(P<0.05).There was no significant difference in the incidence of postoperative complications between the two groups(P>0.05).Conclusion:PFNA-ii intramedullary nail can reduce the surgical trauma,shorten the postoperative recovery time,improve the hip function and reduce the inflammatory reaction of patients with intertrochanteric fracture.
关键词
股骨转子间骨折/PFNA-Ⅱ髓内钉/髋关节功能/血清炎症相关因子/并发症Key words
Femoral intertrochanteric fracture/PFNA-intramedullary nail/Hip joint function/Serum inflammation-related factors/Complications引用本文复制引用
出版年
2024