桉柠蒎肠溶软胶囊治疗慢性鼻窦炎患者的疗效分析
Analysis ofTherapeutic Effect of Eucalyptus Lipinine Enteric Softgel Capsule on Patients with Chronic Sinusitis
吕云勤 1陶应国 1胡高见1
作者信息
- 1. 盐城市亭湖区人民医院耳鼻喉科,江苏盐城 224000
- 折叠
摘要
目的 探讨桉柠蒎肠溶软胶囊治疗慢性鼻窦炎患者的临床效果.方法 选择医院2022年1月-2024年3月收治的慢性鼻窦炎患者80例,以随机数字表法分组,对照组(n=40)使用布地奈得鼻喷雾剂治疗,观察组(n=40)在此基础上加用桉柠蒎肠溶软胶囊治疗.对比两组临床疗效、症状改善时间、炎性指标水平与不良反应发生情况.结果 观察组总有效率较对照组高,差异有统计学意义(P＜0.05).观察组各症状改善时间均较对照组短,差异有统计学意义(P＜0.05).治疗前,两组炎性指标比较,差异无统计学意义(P＞0.05);治疗后,两组血清CRP、TNF-α、IL-6水平均下降,且观察组炎性指标降幅较对照组更大,差异有统计学意义(P＜0.05).两组患者不良反应发生率比较,差异无统计学意义(P＞0.05).结论 桉柠蒎肠溶软胶囊治疗慢性鼻窦炎患者的疗效可靠,可缓解患者症状,减轻炎性反应,且不良反应少.
Abstract
Objective:To explore the clinical effect of eucalyptus and citronella enteric-coated soft capsules in the treatment of chronic sinusitis.Methods:80 patients with chronic sinusitis admitted to our hospital from January 2022 to March 2024 were randomly divided into two groups.The control group(n=40)was treated with budesonide na-sal spray,and the observation group(n=40)was treated with eucalyptus citronella enteric-coated soft capsules.The clinical efficacy,symptom improvement time,inflammatory index level and adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was higher than that of the control group,with statistical significance(P＜0.05).The improvement time of each symptom in the observation group was shorter than that in the control group,with statistical significance(P＜0.05).Before treatment,there was no significant difference in inflammatory indexes between the two groups(P＞0.05).After treatment,the levels of se-rum CRP,TNF-α and IL-6 in both groups decreased,and the decrease of inflammatory indexes in the observa-tion group was greater than that in the control group,with statistical significance(P＞0.05).There was no signifi-cant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion:Eucalyptus Cin-namomum cassia enteric-coated soft capsule has reliable curative effect on patients with chronic sinusitis,which can relieve symptoms and inflammatory reaction with few adverse reactions.
关键词
慢性鼻窦炎/桉柠蒎肠溶软胶囊/疗效/炎性指标/不良反应Key words
Chronic sinusitis/Eucalyptus lime pinine enteric softgel capsules/Curative effect/Inflammatory index/Adverse reaction引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据