ClinicalStudy on the Treatment of Pediatric Influenza Combined with Oseltamivir Phosphate
Objective:To explore the clinical effect of Xiaoer Chiqiao Qingre Granule combined with oseltamivir phos-phate in treating infantile influenza.Methods:Eighty-two children with influenza admitted to tinghu district People's Hospital of Yancheng City from January 2022 to October 2023 were randomly divided into control group and ob-servation group,with 41 cases in each group.The control group was treated with oseltamivir phosphate,while the observation group was treated with Xiaoer Chiqiao Qingre Granule combined with oseltamivir phosphate.The clini-cal effect,symptom improvement time,inflammatory factor level and adverse reactions were compared between the two groups.Results:The total effective rate in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).Compared with the control group,the remission time of each symptom in the observation group was shorter,and the difference was statistically significant(P＜0.05).After treatment,the levels of CRP,TNF-α and IL-6 in both groups decreased,and the levels of inflammatory factors in the observation group were lower,with statistical significance(P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion:Treating children with influenza with Xiaoer Chiqiao Qingre Granule combined with oseltamivir phosphate can accelerate the remission of symptoms,re-duce inflammatory reaction and not increase adverse reactions.
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