ClinicalEfficacy of Moxifloxacin Plus Multidrug Therapy in MDR Tuberculosis and its Effect on Inflammatory Factors Level and Immune Function
Objective:To Objective to explore the clinical effect of moxifloxacin combined with multi-drugs in the treatment of multi-drug resistant pulmonary tuberculosis and its influence on inflammatory factors and immune function.Methods:From February 2021 to November 2023,78 patients with multidrug-resistant pulmonary tuber-culosis in Yangzhou Third People's Hospital were selected and randomly divided into control group and observation group,with 39 cases in each group.The control group was treated with routine chemotherapy,and the observation group was treated with moxifloxacin on the basis of this.The clinical efficacy,inflammatory factors and immune function of the two groups were compared.Results:The total effective rate in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).The levels of inflammatory fac-tors in the observation group were all lower after treatment,and the difference was statistically significant(P＜0.05).After treatment,all immune function indexes in the observation group were better,and the difference was statistically significant(P＜0.05).Conclusion:Moxifloxacin combined with multi-drugs can achieve good curative effect in the treatment of multi-drug resistant pulmonary tuberculosis,and can obviously improve the inflammato-ry response and immune function of patients.
MoxifloxacinMultidrug-resistant pulmonary tuberculosisClinical efficacyInflammatory factorsIm-mune function
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