CorrelationAnalysis of Autoimmune Function in Recurrent Aphthous Stomatitis
Objective:To explore the changes of immune function in patients with recurrent aphthous stomatitis(RAS).Methods:The clinical data of 143 RAS patients(RAS group)and 95 normal people(control group)in the Department of Oral Mucosal Diseases,Affiliated Stomatological Hospital of Nanjing Medical University from Janu-ary 2019 to January 2020 were retrospectively analyzed.Serum IgA、IgG、IgM、IgE、T lymphocyte CD3+、T helper CD4+、T suppressor CD8+and NK CD3-CD(16+)were collected.Results:The average levels of IgM、IgE and IgG in RAS group were higher than those in control group,and the difference was statistically significant(P＜0.05).The average CD4+ratio and CD4/CD8 ratio of T helper cells in RAS group were significantly lower than those in control group,while the average CD8+ratio of T suppressor cells was significantly higher than that in control group,with statistical significance(P＜0.05).Conclusion:The immune function of patients with RAS is different from that of normal people in the course of disease progression,which indicates that there is a certain correlation between immune system disorder and the onset of RAS.
国家科技期刊平台
NSTL
万方数据
