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笔形束质子放疗系统质控中束斑大小测量方法对比研究

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目的 研究对比笔形束质子放疗系统质控中束斑大小的测量方法.方法 使用 Matrixx One二维平面电离室矩阵、Lynx-PT平面闪烁体探测器及XRV-124 锥形闪烁体探测器-三种不同种类、不同形状的探测器对质子放疗系统中不同能量的质子束斑大小进行测量,并将测量结果与加速器验收时束斑大小结果进行对比.结果 Matrixx One的束斑大小测量结果与验收结果相比偏差较大,其中 230 MeV 时的最大偏差达到 41.25%.而Lynx-PT和XRV-124 的束斑测量结果与验收结果相比,最大偏差分别为-7.35%和 3.69%,Lynx-PT测量结果相较于验收结果系统性偏小.结论 Lynx-PT 和 XRV-124 均适用于质子放疗系统束斑大小的测量,Matrixx One适用于束斑尺寸较大的质子放疗系统,相较于 Lynx-PT和 Matrixx One,XRV-124 在旋转治疗室单能单点束斑尺寸测量中更有优势.
Methods for Quality Assurance of Spot size in Pencil Beam scanning Proton Therapy
Objective:This study aimed to compare different methods for measuring spot size for quality assurance in pencil beam scanning proton therapy system.Methods:Three different types of detectors,including Matrixx One two-dimensional plane ionization chamber array,Lynx-PT planar scintillator detector,and XRV-124 conical scintillator detector,were employed to measure spot sizes with different energies in the proton therapy system.The measured results were compared with the spot sizes obtained during commissioning and acceptance testing(CAT).Results:The spot size measurement results using Matrixx One showed significant deviations compared to CAT,with a maximum deviation of 230 MeV spot size at 41.25%.The maximum deviations for Lynx-PT and XRV-124 spot size measurements compared to CAT were-7.35%and 3.69%,respectively.Lynx-PT measurements consistently resulted in smaller spot sizes compared to CAT.Conclusion:Both Lynx-PT and XRV-124 are effective in measur-ing spot size in proton therapy systems,with Matrixx One optimized for larger spot sizes.In contrast,XRV-124,compared to Lynx-PT and Matrixx One,has an advantage in spot size measurement for rotational treatment rooms.

Pencil beam scanning proton therapyQuality assuranceDetectorSpot size

鲍小静、郑多林、张晓强、苏祝平

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中国科学技术大学附属第一医院离子医学中心·合肥离子医学中心,安徽合肥 230088

笔形束质子放疗 质控 探测器 束斑大小

2024

生命科学仪器
北京市北分仪器技术公司

生命科学仪器

影响因子:0.305
ISSN:1671-7929
年,卷(期):2024.22(3)
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