芪参益智颗粒定量测定研究
Study on Quantitative Determination of Qishen Yizhi Granules
赵晨阳 1王贵金2
作者信息
- 1. 河北省药品审评中心,河北石家庄 050000
- 2. 河北省石家庄平安医院有限公司,河北石家庄 050000
- 折叠
摘要
目的 探讨芪参益智颗粒中主要组分五味子的定量测定方法.方法 用 HPLC法测定芪参益智颗粒中五味子醇甲的含量.结果 芪参益智颗粒中五味子醇甲的进样量在 0.1470～1.1572μg,与峰面积呈良好的线性关系.五味子醇甲的平均回收率为 99.45%(n=9),RSD为 0.72%.结论 用 HPLC 法测定芪参益智颗粒中主要组分五味子的含量方法简便、准确,回收率与重现性好,可作为该药物的定量测定方法.
Abstract
Objective:To explore the quantitative determination method of Schisandra chinensis,the main component in Qishen Yizhi granules.Methods:The content of schisandrin A in Qishen Yizhi Granules was determined by HPLC.Results:The sample volume of schisandrin A in Qishen Yizhi Granules was 0.1470～1.1572 μg,which showed a good linear relationship with the peak area.The average recovery rate of schisandrin A was 99.45%(n=9),and RSD was 0.72%.Conclusion:HPLC method is simple、accurate,with good recovery and reproducibility,and can be used as a quantitative method for the determination of the drug.
关键词
芪参益智颗粒/HPLC/定量测定/五味子醇甲Key words
Qishen Yizhi Granules/HPLC/Quantitative determination/Schisandrin引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据