Correlation between Older People with Type 2 Diabetes's Blood CRP、Hcy Levels And Vitamin D Insufficiency
Objective:To explore the correlation between serum levels of C-reactive protein(CRP)and homocysteine(Hcy)and vitamin D deficiency(VDD)in elderly patients with type 2 diabetes mellitus(T2DM).Methods:From September 2018 to August 2022,439 patients with T2DM hospitalized in the Department of Endocrinology of Gansu Pro-vincial People's Hospital were selected as the research objects,and they were divided into two groups:the elderly male group(238 cases)and the elderly female group(201 cases).The prevalence rate of VDD was compared between the two groups.Through correlation analysis and binary Logistic regression analysis,the correlation between the levels of inflam-matory factors CRP and Hcy and VDD was evaluated,and the risk factors of VDD were summarized.Results:Fasting blood glucose(FBG),glycosylated hemoglobin(HbA1c)、C-reactive protein(CRP)and uric acid(UA)were compared between the two groups,P>0.05.The prevalence of VDD in the two groups was compared,P>0.05;The level of serum 25-hydroxyvitamin D[25-(OH)D]was positively correlated with the course of diabetes,and negatively correlated with the levels of CRP、Hcy and PTH.CRP and Hcy are risk factors for VDD,and the course of diabetes mellitus is a protective predictor,P<0.05.Conclusion:Serum CRP and Hcy levels are negatively correlated with 25-(OH)D.Monitoring the levels of CRP and Hcy has certain clinical significance for identifying and intervening VDD.
Type 2 diabetesVitamin D deficiencyHomocysteineC-reactive protein
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