低频磁场治疗对促进脑外伤后患者神经功能恢复的临床研究
Clinical Study of Low-Frequency Magnetic Field Therapy in Promoting the Recovery of Neurological Function in Patients with Traumatic Brain Injury
张昕1
作者信息
- 1. 浙江省中医院神经外科,浙江杭州 310006
- 折叠
摘要
目的 研究分析低频磁场治疗对促进脑外伤后患者神经功能恢复的临床效果.方法 选取 2023 年 3 月至2024 年 1 月在浙江省中医院神经外科进行治疗的脑外伤患者 90 例,随机分为两组.对照组与研究组各 45 例患者.两组入院后,均进行常规治疗,研究组患者在此基础上给予低频磁场治疗,连续治疗 1 个月.对比两组患者的临床治疗效果、治疗前后神经功能及血清神经功能因子水平.结果 相比对照组,研究组临床治疗总有效率较高,P<0.05.治疗前,两组美国国立卫生院卒中量表(NHISS)评分、格拉斯哥昏迷评分法(GCS)评分相比,P>0.05;治疗后,两组GCS评分均增高,NHISS评分均降低,且研究组两项评分变化较对照组均更为明显,P<0.05.治疗前,两组血清胶质细胞源性神经营养因子(GDNF)、脑源性神经营养因子(BDNF)、髓鞘碱性蛋白(MBP)水平相比,P>0.05;治疗后,两组患者血清 GDNF、BDNF水平均增加,血清 MBP 水平均降低,且研究组三项指标变化较对照组均更为明显,P<0.05.结论 低频磁场治疗对脑外伤后患者的疗效显著,可有效调节患者神经功能因子水平,从而促进其神经功能的恢复.
Abstract
Objective:To study and analyze the clinical effect of low-frequency magnetic field therapy on promoting the recovery of neurological function in patients with traumatic brain injury.Methods:From March 2023 to January 2024,90 patients with traumatic brain injury were selected and randomly divided into two groups.45 patients in the control group and 45 patients in the study group.After admission,both groups were given routine treatment,while the patients in the study group were given low-frequency magnetic field treatment for one month.The clinical therapeutic effect、neurological function and serum neurofunctional factors before and after treatment were compared between the two groups.Results:Compared with the control group,the total effective rate of clinical treat-ment in the study group was higher,P<0.05.Before treatment,the scores of National Institutes of Health Stroke Scale(NHISS)and Glasgow Coma Scale(GCS)were compared between the two groups,P>0.05;After treatment,the GCS score increased and the NHISS score decreased in both groups,and the changes of the two scores in the study group were more obvious than those in the control group,P<0.05.Before treatment,the serum levels of glial cell-derived neurotrophic factor(GDNF)、brain-derived neurotrophic factor(BDNF)and myelin basic protein(MBP)in the two groups were compared,P>0.05;After treatment,the serum GDNF and BDNF lev-els in both groups increased,while the serum MBP level decreased,and the changes of the three indexes in the study group were more obvious than those in the control group,P<0.05.Conclusion:Low-frequency magnetic field therapy is effective for patients with traumatic brain injury,which can effectively regulate the level of neurological functional factors and promote the recovery of neurological function.
关键词
低频磁场/脑外伤/神经功能Key words
Low frequency magnetic field/Brain trauma/Neurological function引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据