首页|疏肝消瘰丸治疗肉芽肿性乳腺炎肿块期肝郁痰凝证的临床研究

疏肝消瘰丸治疗肉芽肿性乳腺炎肿块期肝郁痰凝证的临床研究

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目的 研究分析疏肝消瘰丸治疗肉芽肿性乳腺炎(GLM)肿块期肝郁痰凝证的临床效果.方法 选取 2021 年 12月至 2022 年 12 月湖南中医药大学第一附属医院收治的 60 例GLM肿块期肝郁痰凝证患者,采用简单随机法分为对照组与观察组,各 30 例.两种均给予常规治疗,对照组加用甲泼尼龙,观察组加用疏肝消瘰丸.治疗 12 周后,对比两组临床疗效、临床证候积分、疼痛程度、肿块大小及不良反应发生情况.结果 治疗后,两组临床证候积分较治疗前显著降低,且观察组临床证候积分较对照组更低,P<0.05;两组VAS 评分均较治疗前显著降低,P<0.01,但治疗后两组间VAS 评分对比,P>0.05;两组体表肿块直径均较治疗前缩小,且与对照组相比,观察组肿块直径缩小更显著,P<0.01.治疗 12 周后,观察组总有效率高于对照组,P<0.05.两组不良反应对比,P>0.05.结论 对GLM肿块期肝郁痰凝证患者采用疏肝消瘰丸治疗效果显著,可改善患者临床症状,缩小肿块,减轻疼痛,且不增加不良反应.
Clinical Observation on Shugan Xiaoluo Pills in the Treatment of Granulomatous Lobular Mastitis in the Mass Stage of Liver Stagnation And Phlegm Coagulation Type
Objective:To study and analyze the clinical effect of Shugan Xiaolou Pill in treating granulomatous mastitis(GLM)with liver depression and phlegm coagulation syndrome in the mass stage.Methods:From December 2021 to De-cember 2022,60 patients with liver depression and phlegm coagulation syndrome in GLM mass stage were selected and randomly divided into control group and observation group with 30 cases in each group.Both groups were given routine treatment,the control group was given methylprednisolone,and the observation group was given Shugan Xiaoyu Pill.After 12 weeks of treatment,the clinical efficacy、clinical syndrome score、pain degree、mass size and adverse reactions of the two groups were compared.Results:After treatment,the clinical syndrome score of the two groups was significantly lower than that before treatment,and the clinical syndrome score of the observation group was lower than that of the control group,P<0.05;The VAS scores of the two groups were significantly lower than before treatment,P<0.05,but after treatment,the VAS scores of the two groups were compared,P>0.05;The diameter of the body surface mass in both groups was smaller than that before treatment,and the diameter of the mass in the observation group was more significant than that in the control group,P<0.05.After 12 weeks of treatment,the total effective rate of the observationgroup was higher than that of the control group,P<0.05.The adverse reactions of the two groups were compared,P>0.05.Conclusion:Shugan Xiaoluo Pill is effective in treating GLM patients with stagnation of liver-qi and phlegm-coagulation,which can improve the clinical symptoms,reduce the mass and relieve the pain without increasing adverse reactions.

Granulomatous mastitisMass stageSyndrome of liver depression and phlegm coagulationShugan Xiaoyu Pill

焦方敏、胡玉蝶、王晓丽、杨争、胡金辉

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湖南中医药大学第一附属医院,湖南长沙 410021

肉芽肿性乳腺炎 肿块期 肝郁痰凝证 疏肝消瘰丸

湖南省教育厅重点课题湖南省自然科学基因科卫联合项目湖南省自然科学基金面上项目湖南省卫计委一般指导性课题第五批全国中医临床优秀人才湖南省中医药管理局重点课题

23A02952023JJ603462023JJ30470D202304139639湘中医药科教便函[2022]2号C2022020

2024

生命科学仪器
北京市北分仪器技术公司

生命科学仪器

影响因子:0.305
ISSN:1671-7929
年,卷(期):2024.22(3)
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