Value of Contrast-Enhanced Ultrasonography And Color Doppler Ultrasonography Combined with Shear-wave Elastography in Diagnosis of Carotid Artery Injury in Patients with Nasopharyngeal Carcinoma after Radiotherapy
Objective:To analyze the diagnostic value of contrast-enhanced ultrasound and color Doppler ultrasound combined with shear wave elastography in carotid artery injury of nasopharyngeal carcinoma patients after radio-therapy.Methods:From January 2022 to December 2023,100 patients with nasopharyngeal carcinoma diagnosed by histopathological examination in Shaoguan Yuebei People's Hospital were selected.Among them,50 patients re-ceived radiotherapy as the observation group,and 50 patients newly diagnosed without radiotherapy as the control group.The parameters of contrast-enhanced ultrasound,color Doppler ultrasound and shear-wave elastography were compared between the two groups,and the clinical value of contrast-enhanced ultrasound and color Doppler ultrasound combined with shear-wave elastography in the diagnosis of carotid artery injury in nasopharyngeal car-cinoma patients after radiotherapy was analyzed by receiver working curve(ROC).Results:The carotid intima-media thickness,resistance index and stenosis degree in the observation group were higher than those in the control group,P＜0.05.The end-diastolic velocity and peak systolic velocity of carotid artery in observation group were lower than those in control group,P＜0.05.The maximum、minimum and average values of Young's modulus in the observation group were higher than those in the control group,P＜0.05.The sensitivity and specificity of color Doppler ultrasound,shear wave elastography,contrast-enhanced ultrasound and their combination in the diagnosis of carotid artery injury in nasopharyngeal carcinoma patients after radiotherapy were higher than those of single ap-plication,P＜0.05.Conclusion:Contrast-enhanced ultrasound,color Doppler ultrasound and shear wave elastogra-phy are more effective in the diagnosis of carotid artery injury in patients with nasopharyngeal carcinoma after radio-therapy than single application.
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