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托法替布治疗中重度类风湿关节炎的有效性评估

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目的 探究对中重度类风湿关节炎患者使用托法替布治疗的效果.方法 选择2022年8月至2023年8月期间盐城市第一人民医院收治的94例中重度类风湿性关节炎患者,采用抽签法分为参照组(给予常规治疗方案)与观察组(给予常规治疗结合托法替布治疗),各47例.对比两组治疗前后关节功能指标、肾功能指标及炎性因子.结果 观察组治疗后关节功能、肾功能指标及炎性因子均优于参照组,P<0.05.结论 对中重度类风湿关节炎患者使用托法替布治疗的效果更好,有助于改善患者关节功能与肾功能,减轻炎症反应.
Evaluation of the Effectiveness of Tofacitinib in the Treatment of Moderate to Severe Rheumatoid Arthritis
Objective:To explore the therapeutic effect of tofacib on moderate and severe rheumatoid arthritis.Meth-ods:From August 2022 to August 2023,94 patients with moderate and severe rheumatoid arthritis in the First Peo-ple's Hospital of Yancheng City were selected and divided into the reference group(given routine treatment plan)and the observation group(Routine treatment combined with tofacitib was given)by lottery,47 cases each.The in-dexes of joint function,renal function and inflammatory factors were compared between the two groups before and after treatment.Results:After treatment,the joint function、renal function and inflammatory factors in the observa-tion group were better than those in the reference group,P<0.05.Conclusion:Tofatib is more effective in the treat-ment of moderate and severe rheumatoid arthritis,which is helpful to improve joint function and renal function and reduce inflammatory reaction.

TofacitinibModerate to severeRheumatoid arthritisJoint function

卞月存、周芳芳

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盐城市第一人民医院,江苏盐城 224000

托法替布 中重度 类风湿关节炎 关节功能

2024

生命科学仪器
北京市北分仪器技术公司

生命科学仪器

影响因子:0.305
ISSN:1671-7929
年,卷(期):2024.22(5)