首页|小柴胡汤加减与氟哌噻吨美利曲辛治疗老年抑郁症患者的临床效果

小柴胡汤加减与氟哌噻吨美利曲辛治疗老年抑郁症患者的临床效果

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目的 探讨小柴胡汤加减联合氟哌噻吨美利曲辛(黛力新)治疗老年抑郁症患者的临床效果.方法 将2021年1月至2022年12月医院收治的98例老年抑郁症患者,用随机数字表法分成对照组(49例)和研究组(49例).对照组接受基础治疗联合黛力新,研究组在对照组基础上给予小柴胡汤加减治疗.比较两组抑郁程度、睡眠质量、应对方式、临床疗效与不良反应.结果 研究组治疗1周、治疗2周,HAMD-17评分、PSQI评分均低于对照组,P<0.05,SCSQ中积极应对、消极应对评分均高于对照组,P<0.05.研究组治疗总有效率高于对照组,P<0.05.两组不良反应发生率比较,P>0.05.结论 小柴胡汤加减联合黛力新治疗老年抑郁症患者可减轻其抑郁症状,改善睡眠质量和应对方式,提高治疗有效率,且安全性良好.
Clinical Effect of Xiaochaihu Decoction And Flupentixol Meritraxin in the Treatment of Elderly Depression
Objective:To explore the clinical effect of Xiaochaihu decoction combined with droperidol and melitracen(deanxit)in the treatment of elderly patients with depression.Methods:From January 2021 to December 2022,98 elderly patients with depression were randomly divided into control group(49 cases)and research group(49 ca-ses).The control group received basic treatment combined with Deanxit,and the research group was given Xi-aochaihu decoction on the basis of the control group.The degree of depression,sleep quality、coping style、clinical efficacy and adverse reactions were compared between the two groups.Results:After one week and two weeks of treatment,the scores of HAMD-17 and PSQI in the study group were lower than those in the control group,P<0.05,while the scores of positive coping and negative coping in SCSQ were higher than those in the control group,P<0.05.The total effective rate in the study group was higher than that in the control group,P<0.05.The inci-dence of adverse reactions between the two groups was compared,P>0.05.Conclusion:Modified Xiaochaihu Decoc-tion combined with Deanxit can relieve the depressive symptoms of elderly patients with depression,improve their sleep quality and coping style,improve the treatment efficiency and have good safety.

Senile depressionXiaochaihu decoctionFlupentixol melitracenSleep qualityCoping style

方源、李荣新

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上海市浦东新区三林康德社区卫生服务中心,上海 200124

上海市复旦大学附属金山医院,上海 201508

老年抑郁症 小柴胡汤 氟哌噻吨美利曲辛 睡眠质量 应对方式

2024

生命科学仪器
北京市北分仪器技术公司

生命科学仪器

影响因子:0.305
ISSN:1671-7929
年,卷(期):2024.22(5)