首页|肿瘤标志物CA19-9、CEA水平与胆囊结石伴胆囊炎患者胆红素水平的相关性分析

肿瘤标志物CA19-9、CEA水平与胆囊结石伴胆囊炎患者胆红素水平的相关性分析

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目的 分析肿瘤标志物CA19-9、CEA水平与胆囊结石伴胆囊炎患者胆红素水平的相关性.方法 回顾性分析2023年1月至2024年5月期间医院收治的104例胆囊结石伴胆囊炎患者,为观察组,将同期在医院体检中心进行健康体检的104例健康者作为对照组.收集两组血清标本,检测血清CA19-9、CEA、TBIL及DBIL水平,分析CA19-9、CEA水平与胆囊结石伴胆囊炎患者胆红素水平的相关性.结果 观察组CEA水平与对照组对比,P>0.05;观察组CA19-9、TBIL及DBIL水平均分别高于对照组,P<0.05;经过治疗,观察组CA19-9、CEA、TBIL及DBIL水平均较治疗前显著降低,P<0.05.观察组血清CA19-9、CEA水平与TBIL及DBIL水平呈正相关.结论 胆结石伴胆囊炎患者血清CA119-9、TBIL及DBIL水平均呈现上升的趋势,且CA19-9、CEA与胆红素水平呈正相关,可用于胆结石或胆道疾病的诊断及病情评估.
Correlation between Tumor Markers CA19-9 and CEA Levels And Bilirubin Levels in Patients with Gallstones And Cholecystitis
Objective:To analyze the correlation between tumor markers CA19-9 and CEA levels and bilirubin levels in pa-tients with gallstones and cholecystitis.Methods:A retrospective analysis was made on 104 patients with gallstones and cholecystitis admitted to the hospital from January 2023 to May 2024.As the observation group,104 healthy people who underwent physical examination in the hospital physical examination center during the same period served as the control group.Serum samples were collected from two groups,and serum levels of CA19-9、CEA、TBIL and DBIL were detec-ted,and the correlation between CA19-9、CEA levels and bilirubin levels in patients with gallstones and cholecystitis was analyzed.Results:Compared with the control group,the CEA level in the observation group was,P>0.05.The levels of CA19-9、TBIL and DBIL in the observation group were higher than those in the control group,respectively,P<0.05;Af-ter treatment,the levels of CA19-9、CEA、TBIL and DBIL in the observation group were significantly lower than those before treatment,P<0.05.The levels of serum CA19-9 and CEA in the observation group were positively correlated with the levels of TBIL and DBIL.Conclusion:The serum levels of CA119-9、TBIL and DBIL in patients with cholelithia-sis and cholecystitis are on the rise,and CA19-9 and CEA are positively correlated with bilirubin levels,which can be used for the diagnosis and condition evaluation of cholelithiasis or biliary diseases.

Tumor markersCarbohydrate antigenCarcinoembryonic antigenGallbladder stonesCholecystitis

莫丽锦、林发全

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广西高校临床检验重点实验室,广西 南宁 530021

河池市人民医院医学检验科,广西 河池 547000

广西医科大学第一附属医院检验科,广西 南宁 530021

肿瘤标志物 糖类抗原 癌胚抗原 胆囊结石 胆囊炎

2024

生命科学仪器
北京市北分仪器技术公司

生命科学仪器

影响因子:0.305
ISSN:1671-7929
年,卷(期):2024.22(6)