首页|腹腔镜完全腹膜外疝修补术对腹股沟疝患者炎症介质与氧化应激及疼痛介质的影响

腹腔镜完全腹膜外疝修补术对腹股沟疝患者炎症介质与氧化应激及疼痛介质的影响

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目的 探讨采用腹腔镜完全腹膜外疝修补术(TEP)治疗腹股沟疝的效果及对炎症介质、氧化应激与疼痛介质的影响.方法 选择80例2022年1月至2023年12月在湛江中心人民医院接受手术治疗的腹股沟疝患者,采用随机数表法分为开放组和TEP组,每组40例.开放组接受开放式疝修补术,TEP组接受TEP手术.观察对比两组总体效果.结果 TEP组手术指标、术后并发症发生率优于开放组,手术后1 d炎症介质、氧化应激、疼痛介质均优于开放组(P<0.05).结论 与开放式疝修补手术相比,TEP具有并发症少、创伤小、康复快的优点,且对炎症反应、氧化应激及痛觉的影响均更小.
Effects of Laparoscopic Total Extraperitoneal Hernia Repair on Inflammatory Mediators、Oxidative Stress And Pain Mediators in Patients with Inguinal Hernia
Objective:To explore the effect of laparoscopic total extraperitoneal hernia repair(TEP)on inguinal her-nia and its influence on inflammatory mediators,oxidative stress and pain mediators.Methods:Eighty patients with inguinal hernia who underwent surgical treatment in Zhanjiang Central People's Hospital from January 2022 to De-cember 2023 were randomly divided into open group and TEP group,with 40 cases in each group.Open group re-ceived open hernia repair and TEP group received TEP operation.Observe and compare the overall effect of the two groups.Results:The operative indexes and postoperative complications in TEP group were better than those in open group、and the inflammatory mediators、oxidative stress and pain mediators were better than those in open group 1 day after operation(P<0.05).Conclusion:Compared with open hernia repair,TEP has the advantages of less com-plications,less trauma and faster recovery,and has less influence on inflammatory reaction,oxidative stress and pain.

Inguinal herniaLaparoscopic complete repair of extraperitoneal herniaInflammatory mediatorsOxi-dative stressPain mediators

许成裘、蔡观河、王扩杰、曹展祯、严聪

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湛江中心人民医院普外三科,广东 湛江 524033

腹股沟疝 腹腔镜完全腹膜外疝修补术 炎症介质 氧化应激 疼痛介质

2024

生命科学仪器
北京市北分仪器技术公司

生命科学仪器

影响因子:0.305
ISSN:1671-7929
年,卷(期):2024.22(6)