首页|肌钙蛋白T、超敏-C反应蛋白、D-二聚体在鉴别诊断心源性胸痛中的应用价值

肌钙蛋白T、超敏-C反应蛋白、D-二聚体在鉴别诊断心源性胸痛中的应用价值

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目的 研究肌钙蛋白T(cTnT)、超敏-C反应蛋白(hs-CRP)、D-二聚体(D-D)在鉴别诊断心源性胸痛(CCP)中的应用价值.方法 选取2023年1月至2023年12月期间南方医科大学顺德医院(佛山市顺德区第一人民医院)诊治的100例急性胸痛患者,根据病因分为心源性胸痛组(CCP组,n=57)与非心源性胸痛组(NCCP组,n=43).对两组患者的cTnT、hs-CRP、D-D进行检测,比较上述指标表达水平,并采用ROC曲线分析各指标对CCP的诊断效能.结果 CCP组cTnT、hs-CRP、D-D表达水平均高于NCCP组,P<0.05;ROC曲线结果显示,cTnT、hs-CRP、D-D单独检测诊断CCP的AUC分别为0.799、0.761、0.854,三者联合检测的AUC为0.929,敏感性、特异性相对更高(P<0.05).结论 cTnT、hs-CRP、D-D联合检测在早期鉴别诊断CCP中具有较高的应用价值.
ApplicationValue of Troponin T、High-sensitivity C-reactive Protein And D-dimer in Differential Diagnosis of Cardiogenic Chest Pain
Objective:To study the value of troponin T(cTnT)、high-sensitivity C-reactive protein(hs-CRP)and D-dimer(D-D)in differential diagnosis of cardiogenic chest pain(CCP).Methods:100 patients with acute chest pain diagnosed and treated in Shunde Hospital of Southern Medical University(First People's Hospital of Shunde District,Foshan City)were selected and divided into cardiogenic chest pain group(CCP group,n=57)and noncar-diac chest pain group(NCCP group,n=43)according to the etiology.CTnT、hs-CRP and D-D were detected in the two groups,and the expression levels of the above indexes were compared,and the diagnostic efficacy of each in-dex for CCP was analyzed by ROC curve.Results:The expression levels of cTnT、hs-CRP and D-D in CCP group were higher than those in NCCP group,P<0.05.The ROC curve showed that the AUC of cTnT、hs-CRP and D-D in the diagnosis of CCP were 0.799、0.761 and 0.854 respectively,and the AUC of the combined detection of CT-NT、HS-CRP and D-D was 0.929,which was relatively higher in sensitivity and specificity(P<0.05).Conclu-sion:the combined detection of cTnT、hs-CRP and D-D has high application value in early differential diagnosis of CCP.

Troponin THypersensitivity-C reactive proteinD-dimerAcute chest painDiagnostic value

方创波、刘书雁、赖才明

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南方医科大学顺德医院(佛山市顺德区第一人民医院)急诊科,广东 佛山 528300

肌钙蛋白T 超敏-C反应蛋白 D-二聚体 急性胸痛 诊断价值

2024

生命科学仪器
北京市北分仪器技术公司

生命科学仪器

影响因子:0.305
ISSN:1671-7929
年,卷(期):2024.22(6)