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抗生素合理应用情况分析与循证药学的应用价值

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目的 探讨循证药学(EBP)对促进抗生素合理应用的价值.方法 选择北京市丰台区中医医院(北京市丰台区南苑医院)2023年1月至6月开展EBP管理前随机抽检的2000张抗生素处方、2023年7月至12月开展EBP管理后随机抽检的2000张抗生素处方作为研究对象.对比开展EBP管理前后医院抗生素合理应用情况.结果 开展EBP管理后,医院抗生素合理用药情况得到显著提升,抽检不合理处方率、抗生素联合用药率、预防性用药率均较开展EBP管理前显著下降(P<0.05).开展EBP管理后,医师对抗菌药物的认知明显好于开展前(P<0.05).开展EBP管理后,统计发现用药不良反应率仅为1.10%,明显低于开展EBP管理前的5.70%(P<0.05).结论 开展EBP管理对促进抗生素合理应用、提高医师对抗菌药物的认知,从而减少用药不良反应具有积极意义.
To Study the Application Value of Rational Application of Antibiotics And Evidence-based Pharmacy
Objective:To explore the value of evidence-based pharmacy(EBP)in promoting the rational use of anti-biotics.Methods:2000 antibiotic prescriptions randomly selected from Beijing Fengtai Traditional Chinese Medicine Hospital(Beijing Fengtai Nanyuan Hospital)before EBP management from January to June 2023 and 2000 antibi-otic prescriptions randomly selected after EBP management from July to December 2023 were selected as the re-search objects.To compare the rational use of antibiotics in hospitals before and after EBP management.Results:Af-ter EBP management,the rational use of antibiotics in the hospital was significantly improved,and the rate of irra-tional prescription,combined use of antibiotics and preventive use were significantly lower than before EBP manage-ment(P<0.05).After EBP management,doctors'knowledge of antibacterial drugs was significantly better than be-fore(P<0.05).After EBP management,it was found that the adverse drug reaction rate was only 1.10%,which was significantly lower than 5.70%before EBP management(P<0.05).Conclusion:EBP management is of posi-tive significance to promote the rational use of antibiotics,improve doctors'knowledge of antibacterial drugs,and thus reduce adverse drug reactions.

Evidence based pharmaceutical managementReasonable use of antibioticsPreventive medicationAd-verse drug reactions

胡明芳、孟欣、杨轶

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北京市丰台区中医医院(北京市丰台区南苑医院),北京 100076

循证药学管理 抗生素合理应用 预防性用药 用药不良反应

2024

生命科学仪器
北京市北分仪器技术公司

生命科学仪器

影响因子:0.305
ISSN:1671-7929
年,卷(期):2024.22(6)