首页|Protective effects of oleic acid and polyphenols in extra virgin olive oil on cardiovascular diseases
Protective effects of oleic acid and polyphenols in extra virgin olive oil on cardiovascular diseases
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The Mediterranean diet has long been recognized as one of the most effective ways to prevent and improve cardiovascular disease.Extra virgin olive oil(EVOO)is the typical sources of fat in the Mediterranean diet which have been shown to have noteworthy nutritional value and positive impact on human health.It is worth noting that EVOO owes its superior nutritional value to its bioactive composition.The main component of EVOO is monounsaturated fatty acids(MUFAs)in the form of oleic acid.Oleic acid accounts for up to 70％-80％of EVOO.Secondly,EVOO contains approximately more than 30 phenolic compounds,of which HT is essential for the protection against cardiovascular diseases.In this review,we focused on the potential mechanisms of oleic acid and polyphenols combat cardiovascular diseases risk in terms of oxidative stress,inflammation,blood pressure,endothelial function and cholesterol.This review might provide a reference for the studies on cardiovascular protective effects of EVOO.
Yan Lu、Jun Zhao、Qiqi Xin、Rong Yuan、Yu Miao、Manli Yang、Hui Mo、Keji Chen、Weihong Cong
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Laboratory of Cardiovascular Diseases,Xiyuan Hospital of China Academy of Chinese Medical Sciences,Beijing 100091,China
National Clinical Research Center for Chinese Medicine Cardiology,Beijing 100091,China
Traditional Chinese Medicine Department,The Affiliated Hospital of Qingdao University,Qingdao 266000,China
Nanjing University of Chinese Medicine,Nanjing 210023,China
Health Bureau of the Government of the Macao Special Administrative Region,Macao 999078,China
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CACMS Innovation FundBeijing NovaprogramOpening Project of the Key Laboratory of Integrative Chinese and Western Medicine for the Diagnosis and Treatment of Circula国家自然科学基金
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