Diet and physical activity influence the composition of gut microbiota,benefit on Alzheimer's disease

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外文摘要：Alzheimer's disease is a neurodegenerative disease with complex etiology.Gut microbiota influences the gut-brain axis,which may affect pathways related to the pathogenesis of Alzheimer's disease.Additionally,diet and physical activity are likely to affect the pathology of Alzheimer's disease as well as the gut microbiota.This demonstrates that it may be possible to prevent or halt the progression of Alzheimer's disease by regulating the gut microbiota using diet and physical activity strategies.Therefore,the present study reviews the association between these two interventions and gut microbiota in the human body.It also summarizes how these two interventions benefit Alzheimer's disease.Furthermore,the primary limitations of these two interventions are discussed and promising strategies are proposed,which may be beneficial to further study and develop the intervening measure for the progression of Alzheimer's disease.

外文关键词：

Alzheimer's diseaseGut microbiotaBrain-gut axisDietPhysical activity

作者：

Jinyue Zhou、Min Tang、Wanyi Li、Rui Fang、Chunlan Tang、Qinwen Wang

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作者单位：

School of Public Health,Health Science Center,Ningbo University,Ningbo 315211,China

Department of Neurology,Ningbo Rehabilitation Hospital,Ningbo 3151000,China

Ningbo Institute of Life and Health Industry,University of Chinese Academy of Sciences,Ningbo 315100,China

基金：

国家自然科学基金major fund project of Ningbo Science and Technology BureauOpenedend Fund of Key LaboratoryOpenedend Fund of Key LaboratoryPublic Project of NingboProject of YinzhouNingbo Rehabilitation HospitalK.C.Wong Magna Fund in Ningbo University

项目编号：

321710352019B10034KFJJ-202101ZPKLP202202202002N31672022AS0252022KY02

出版年：

2024

DOI：

10.26599/FSHW.2022.9250049

食品科学与人类健康(英文)

CSTPCD

ISSN：

年,卷(期)：2024.13(2)

参考文献量179