A novel AgNPs/MOF substrate-based SERS sensor for high-sensitive on-site detection of wheat gluten

Linglin Fu ¹Yanzhuo Du ¹Jinru Zhou ²Huan Li ¹Minzi Wang ³Yanbo Wang¹

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作者信息

1. Food Safety Key Laboratory of Zhejiang Province,School of Food Science and Biotechnology,Zhejiang Gongshang University,Hangzhou 310018,China
2. Food Safety Key Laboratory of Zhejiang Province,School of Food Science and Biotechnology,Zhejiang Gongshang University,Hangzhou 310018,China;Zhejiang Engineering Research Institute of Food & Drug Quality and Safety,School of Management and E-Business,Zhejiang Gongshang University,Hangzhou 310018,China
3. Zhejiang Dien Biotech Co.,Ltd.,Hangzhou 310030,China
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Abstract

Gluten,known as the major allergen in wheat,has gained increasing concerns in industrialized countries,resulting in an urgent need for accurate,high-sensitive,and on-site detection of wheat gluten in complex food systems.Herein,we proposed a silver nanoparticles(AgNPs)/metal-organic framework(MOF)substrate-based surface-enhanced Raman scattering(SERS)sensor for the high-sensitive on-site detection of wheat gluten.The detection occurred on the newly in-situ synthesized AgNPs/MOF-modified SERS substrate,providing an enhancement factor(EF)of 1.89 × 105.Benefitting from the signal amplification function of AgNPs/MOF and the superiority of SERS,this sensor represented high sensitivity performance and a wide detection range from 1 × 10-15 mol/L to 2 × 106 mol/L with a detection limit of 1.16 × 10-16 mol/L,which allowed monitoring the trace of wheat gluten in complex food system without matrix interference.This reliable sandwich SERS sensor may provide a promising platform for high-sensitive,accurate,and on-site detection of allergens in the field of food safety.

Key words

Wheat allergy/Gluten/Surface-enhanced Raman scattering/Metal-organic framework/DNA recognition

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基金项目

浙江省自然科学基金(LY21C200008)

出版年

2024

食品科学与人类健康(英文)

CSTPCD

ISSN：

参考文献量37

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