The in vitro digestion fates of diacylglycerol under different intestinal conditions:a potential lipid source for lipid indigestion patients

Qingqing Xu ¹Weifei Wang ²Dongxiao Sun-Waterhouse ³Qian Zou ¹Menglei Yan ¹Xuan Liu ¹Dongming Lan ¹Yonghua Wang⁴

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作者信息

1. School of Food Science and Engineering,South China University of Technology,Guangzhou 510640,China
2. Sericultural and Agri-Food Research Institute,Guangdong Academy of Agricultural Sciences,Guangzhou 510610,China
3. School of Food Science and Engineering,South China University of Technology,Guangzhou 510640,China;School of Chemical Sciences,The University of Auckland,Private Bag 92019,New Zealand
4. School of Food Science and Engineering,South China University of Technology,Guangzhou 510640,China;Guangdong Youmei Institute of Intelligent Bio-manufacturing Co.,Ltd.,Foshan 528200,China
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Abstract

The in vitro digestion models mimicking the gastrointestinal(GI)tract of general population and lipid indigestion patients(with lower levels of bile salts or pancreatic lipase)were selected to investigate whether diacylglycerols(DAGs)are potential good lipid sources for these patients.Linseed oil-based DAG(LD)and linseed oil(LT)were selected.LD-based emulsion((83.74±1.23)％)had higher lipolysis degree than LT-based emulsion((74.47±1.16)％)when monitoring the GI tract of normal population as previously reported.Indigestion conditions seriously decreased the digestive degree of LT-based emulsion((40.23±2.48)％-(66.50±3.70)％)while showed less influence on LD-based emulsion((64.18±2.41)％-(81.85±3.45)％).As opposed to LT-based emulsion,LD-based emulsion exhibited preference for releasing unsaturated fatty acids(especially oleic acid and a-linolenic acid)due to their different glycerolipid compositions.LD-based emulsion showed potential for providing lipids and nutrients(including essential fatty acids)for lipid indigestion patients.

Key words

Diacylglycerol/In vitro digestion/Lipolysis level/Cholestatic/Exocrine pancreatic insufficiency

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基金项目

国家重点研发计划(2022YFC2805100)

National Science Fund for Key Program of National Natural Science Foundation of China(31930084)

国家杰出青年科学基金(31725022)

现代农业产业技术体系建设项目(CARS-18-ZJ0503)

Guangdong Provincial Key Research and Development Programme(2022B0202010002)

Science and Technology Innovation Project of Foshan City(FSOAA-KJ919-4402-0013)

出版年

2024

食品科学与人类健康(英文)

CSTPCD

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参考文献量44

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