首页|The in vitro digestion fates of diacylglycerol under different intestinal conditions:a potential lipid source for lipid indigestion patients

The in vitro digestion fates of diacylglycerol under different intestinal conditions:a potential lipid source for lipid indigestion patients

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The in vitro digestion models mimicking the gastrointestinal(GI)tract of general population and lipid indigestion patients(with lower levels of bile salts or pancreatic lipase)were selected to investigate whether diacylglycerols(DAGs)are potential good lipid sources for these patients.Linseed oil-based DAG(LD)and linseed oil(LT)were selected.LD-based emulsion((83.74±1.23)％)had higher lipolysis degree than LT-based emulsion((74.47±1.16)％)when monitoring the GI tract of normal population as previously reported.Indigestion conditions seriously decreased the digestive degree of LT-based emulsion((40.23±2.48)％-(66.50±3.70)％)while showed less influence on LD-based emulsion((64.18±2.41)％-(81.85±3.45)％).As opposed to LT-based emulsion,LD-based emulsion exhibited preference for releasing unsaturated fatty acids(especially oleic acid and a-linolenic acid)due to their different glycerolipid compositions.LD-based emulsion showed potential for providing lipids and nutrients(including essential fatty acids)for lipid indigestion patients.

DiacylglycerolIn vitro digestionLipolysis levelCholestaticExocrine pancreatic insufficiency

Qingqing Xu、Weifei Wang、Dongxiao Sun-Waterhouse、Qian Zou、Menglei Yan、Xuan Liu、Dongming Lan、Yonghua Wang

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School of Food Science and Engineering,South China University of Technology,Guangzhou 510640,China

Sericultural and Agri-Food Research Institute,Guangdong Academy of Agricultural Sciences,Guangzhou 510610,China

School of Chemical Sciences,The University of Auckland,Private Bag 92019,New Zealand

Guangdong Youmei Institute of Intelligent Bio-manufacturing Co.,Ltd.,Foshan 528200,China

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国家重点研发计划National Science Fund for Key Program of National Natural Science Foundation of China国家杰出青年科学基金现代农业产业技术体系建设项目Guangdong Provincial Key Research and Development ProgrammeScience and Technology Innovation Project of Foshan City

2022YFC28051003193008431725022CARS-18-ZJ05032022B0202010002FSOAA-KJ919-4402-0013

2024

10.26599/FSHW.2022.9250139

食品科学与人类健康(英文)

食品科学与人类健康(英文)

CSTPCD
ISSN：
年,卷(期)：2024.13(2)
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