The metabolic profiling of Chinese yam fermented by Saccharomyces boulardii and the biological activities of its ethanol extract in vitro

Xue Li ¹Yiwen Shao ²Limin Hao ³Qiaozhen Kang ²Xiaolong Wang ⁴Jiaqing Zhu ¹Changcheng Zhao ¹Yanling Shi ¹Jike Lu ¹Juanjuan Yi¹

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作者信息

1. School of Life Sciences,Zhengzhou University,Zhengzhou 450001,China;Food Laboratory of Zhongyuan,Zhengzhou University,Luohe 462300,China
2. School of Life Sciences,Zhengzhou University,Zhengzhou 450001,China
3. Systems Engineering Institute,Academy of Military Sciences(AMS),Beijing 100010,China
4. Henan Yinfeng Biological Engineering Technology Co.,Ltd.,Zhengzhou 450000,China
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Abstract

Chinese yam(Dioscorea opposita Thunb.),as one of the medicinal and edible homologous plants,is rich in various nutrients and functional factors.In this study,Chinese yam fermented by Saccharomyces boulardii was performed to investigate its bioactive components and metabolic profile.And then,the main bioactive components and biological activities of fermented Chinese yam ethanol extract(FCYE)were evaluated.Results showed that there were 49 up-regulated metabolites and 52 down-regulated metabolites in fermented Chinese yam compared to unfermented Chinese yam.Besides,corresponding metabolic pathways analysis initially revealed that the distribution of bioactive substances was concentrated on alcohol-soluble small molecular substances.Ulteriorly,the total polyphenol content and the total flavonoid content in FCYE were significantly increased,and the corresponding antioxidant and immunomodulatory activities in vitro were also significantly enhanced.Our study provided a new reference for the comprehensive utilization of Chinese yam and laid a theoretical foundation for the development and application of natural probiotic-fermented products.

Key words

Chinese yam/Saccharomyces boulardii/Metabolites/Antioxidant/Immunomodulation

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基金项目

National Natural Science Foundation of China(32172211)

Natural Science Foundation of Henan Province for Outstanding Youth,China(202300410365)

National Key Research and Development Program of China(2022YFF1103300)

Program for Science and Technology Innovation Talents in Universities of Henan Province(22HASTIT037)

Technology Development(Cooperation)project of Zhengzhou University(20210442A)

Technology Development(Cooperation)project of Zhengzhou University(20210327A)

出版年

2024

食品科学与人类健康(英文)

CSTPCD

ISSN：

段落导航