Structural identification and antioxidative activity evaluation of flaxseed lignan macromolecules:structure-activity correlation

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外文摘要：Flaxseed lignan macromolecules(FLM)are a class of important secondary metabolites in flaxseed,which have been widely concerned due to their biological and pharmacological properties,especially for their antioxidative activity.For the composition and structure of FLM,our results confirmed that ferulic acid glycoside(FerAG)was directly ester-linked with herbacetin diglucoside(HDG)or pinoresinol diglucoside(PDG),which might determine the beginning of FLM biosynthesis.Additionally,p-coumaric acid glycoside(CouAG)might determine the end of chain extension during FLM synthesis in flaxseed.FLM exhibited higher antioxidative activity in polar systems,as shown by its superior 1,1-diphenyl-2-picrylhydrazyl(DPPH)free radical scavenging capacity compared to the 2,2'-azinobis(3-ehtylbenzothiazolin-6-sulfnic acid)(ABTS)cation free radical scavenging capacity in non-polar systems.Moreover,the antioxidative activity of FLM was found to be highly dependent on its composition and structure.In particular,it was positively correlated with the number of phenolic hydroxyl groups(longer FLM chains)and inversely related to the steric hindrance at the ends(lower levels of FerAG and CouAG).These findings verified the potential application of FLM in non-polar systems,particularly in functional food emulsions.

外文关键词：

Flaxseed lignan macromoleculesComposition structureAntioxidative activityStructure-activityCorrelation

作者：

Chen Cheng、Lei Wang、Xiao Yu、Fenghong Huang、Jing Yang、Fang Geng、Xiaoyang Xia、Xia Xiang、Shufang Xu、Qianchun Deng

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作者单位：

Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences,Oil Crops and Lipids Process Technology National & Local Joint Engineering Laboratory,Hubei Key Laboratory of Lipid Chemistry and Nutrition,and Key Laboratory of Oilseeds Processing,Ministry of Agriculture and Rural Affairs,Wuhan 430062,China

College of Food and Bioengineering,Zhengzhou University of Light Industry,Zhengzhou 450002,China

Key Laboratory of Coarse Cereal Processing(Ministry of Agriculture and Rural Affairs),School of Food and Biological Engineering,Chengdu University,Chengdu 610106,China

Clinical Nutrition Department,the Central Hospital of Wuhan,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China

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出版年：

2024

DOI：

10.26599/FSHW.2023.9250009

食品科学与人类健康(英文)

CSTPCD

ISSN：

年,卷(期)：2024.13(6)