首页|Dietary(poly)phenol intake is associated with cardiometabolic health parameters in adolescents

Dietary(poly)phenol intake is associated with cardiometabolic health parameters in adolescents

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The protective role of(poly)phenols against metabolic disorders has been extensively studied in adults but not in adolescents.To assess associations of dietary(poly)phenols and their subclasses with cardiometabolic health parameters in adolescents.A cross-sectional study was conducted in 944 individuals aged 11-14 years enrolled in the SI!Program for Secondary Schools trial(NCT03504059).(Poly)phenol intake was assessed using semi-quantitative food frequency questionnaires and the Phenol-Explorer database.The measured cardiometabolic parameters were waist circumference(WC)age-sex Z-score,blood pressure(BP)age-sex Z-score,blood glucose(BG),triglycerides(TG),and high-density lipoprotein cholesterol(HDL-c).Multilevel mixed-effect linear regression models were applied to examine the association between(poly)phenol quintiles and cardiometabolic health parameters.Compared to the lowest quintile,adolescents in the highest quintile of total(poly)phenol intake had lower WC Z-scores,mean arterial pressure Z-scores,and HDL-c after multivariable adjustment.The WC Z-scores and HDL-c were lower in the highest quintile of flavonoid intake compared to the lowest quintile.The highest quintile of phenolic acid intake was associated with a lower WC Z-score and TG levels,and the highest quintile of stilbene intake with lower BG and TG,and with higher HDL-c compared to the lowest quintile.A higher intake of(poly)phenols,especially flavonoids,phenolic acids,and stilbenes,was associated with better cardiometabolic parameters in adolescents.

PhytochemicalResveratrolLignanFlavan-3-olsAnthocyaninCardiovascular healthTeenagers

Emily P.Laveriano-Santos、Sara Castro-Barquero、Camila Arancibia-Riveros、Ana María Ruiz-León、Rosa Casas、Ramón Estruch、Patricia Bodega、Mercedes de Miguel、Amaya de Cos-Gandoy、Jesús Martínez-Gómez、Gloria Santos-Beneit、Juan M.Fernández-Alvira、Rodrigo Fernández-Jiménez、Rosa M.Lamuela-Raventós、Anna Tresserra-Rimbau

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Department de Nutrició,Ciències de l'Alirnentació I Gastronomia,XIA,Facultat de Farmàcia i Ciències de l'alimentació,Institut de Recerca en Nutrició i Seguretat Alimentària(INSA-UB),Universitat de Barcelona,Barcelona 08028,Spain

Consorcio CIBER,M.P.Fisiopatología de la Obesidad y Nutrición(CIBERObn),Instituto de Salud Carlos Ⅲ(ISCⅢ),Madrid 28029,Spain

Department of Internal Medicine,Hospital Clínic,Institutd'Investigacions Biomèdiques August Pi I Sunyer(IDIBAPS),University of Barcelona,Barcelona 08036,Spain

Mediterranean Diet Foundation,Barcelona 08021,Spain

Foundation for Science,Health and Education(SHE),Barcelona 08008,Spain

Centro Nacional de Investigaciones Cardiovasculares(CNIC),Madrid 28029,Spain

The Zena and Michael A.Wiener Cardiovascular Institute,Icahn School of Medicine at Mount Sinai,New York 10029,USA

CIBER de Enfermedades Cardiovasculares(CIBERCV),Madrid 28029,Spain

Hospital Universitario Clínico San Carlos,Madrid 28040,Spain

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2024

10.26599/FSHW.2023.9250023

食品科学与人类健康(英文)

食品科学与人类健康(英文)

CSTPCD
ISSN：
年,卷(期)：2024.13(6)