首页|Association of hypertension and plant-based dietary patterns on cognitive impairment:a nationwide cohort study in China

Association of hypertension and plant-based dietary patterns on cognitive impairment:a nationwide cohort study in China

扫码查看
原文链接
  • 万方数据
This study investigated the association of hypertension with cognitive impairment and determined whether better adherence to plant-based diet(PBD)patterns may modify the association.We analyzed 4 485 elderly individuals with normal cognition at baseline from the Chinese Longitudinal Healthy Longevity Survey(2011-2018).Cognitive function was assessed by the Mini-mental State Examination(MMSE),and cognitive impairment was defined as an MMSE score below 18 points.Diet patterns were assessed using the overall plant-based diet index(PDI),healthful plant-based diet index(hPDI),and unhealthful plant-based diet index(uPDI)derived from a simplified food frequency questionnaire(FFQ).Blood pressure was measured through physical examination.Cox proportional hazard regression and restricted cubic spline were performed.Participants with hypertension had an increased risk of cognitive impairment compared with normal group.The associations between hypertension and cognitive impairment were more pronounced among participants with lower PDI than those with higher PDI,among participants with lower hPDI than those with higher hPDI,and among participants with higher uPDI than those with lower uPDI.A healthful PBD pattern may attenuate hypertension-induced cognitive impairment,while an unhealthful PBD pattern may exacerbate hypertension-induced cognitive impairment in elderly.Adherence to healthful PBD pattern could be used to prevent or mitigate adverse neurological effects in the hypertensive population.

Cognitive impairmentHypertensionPlant-based dietary patternChinese older adultsCohort

Fang Liang、Jialin Fu、Gabrielle Turner-McGrievy、Yechuang Wang、Kai Ding、Jing Zeng、Justin B Moore、Rui Li

展开 >

School of Public Health,Wuhan University,Wuhan 430071,China

Chengdu High-tech Zone Center for Diseases Control and Prevention,Chengdu 610000,China

Department of Health Promotion,Education,and Behavior Arnold School of Public Health,University of South Carolina,Columbia 29208,USA

Department of Implementation Science,Division of Public Health Sciences,Wake Forest School of Medicine,Winston-Salem 27101,USA

School of Nursing,Wuhan University,Wuhan 430071,China

展开 >

2024

10.26599/FSHW.2023.9250037

食品科学与人类健康(英文)

食品科学与人类健康(英文)

CSTPCD
ISSN：
年,卷(期)：2024.13(6)